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Moderna misses in Q4, stock does what it’s done for nearly 8 months straight: goes down

Moderna’s main revenue driver, the COVID-19 vaccine, is bringing in a fraction of what it used to.

J. Edward Moreno

Moderna shares slipped in early trading after the vaccine maker missed Wall Street estimates.

Moderna reported a $2.91 loss per share, compared to the $2.68 loss per share analysts polled by FactSet were expecting. It reported about $1 billion in sales, above the $943 million analysts expected. Its profits were impacted by an unexpected $238 million charge for a canceled manufacturing contract during the quarter.

Moderna and Pfizer were given government contracts to quickly produce a COVID-19 vaccine in 2020. But Moderna’s portfolio is less diverse than Pfizer’s, and the COVID-19 vaccine remains its top revenue driver even as demand dwindles.

Moderna said last month that it expects to post between $1.5 billion and $2.5 billion of revenue in 2025, compared with the nearly $3 billion analysts expected prior to the guidance.

Moderna’s stock got a bump in January after Oracle Chairman Larry Ellison said at a White House presser that artificial intelligence has the potential to make personalized vaccines to detect and prevent cancer. Though not named, the drugmaker happens to be working on exactly that kind of technology.

Growing concern over bird flu has also given investors optimism for Moderna. Last month (prior to President Trump taking office), Moderna was awarded $590 million from the Department of Health and Human Services to help develop a vaccine to protect humans from bird flu. On Thursday, Trumps pick to run HHS, vaccine skeptic Robert F. Kennedy Jr., was confirmed to run the agency.

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Alaska Airlines dips following weaker-than-expected 2026 earnings guidance

Alaska Airlines, America’s fifth-largest airline, reported its fourth-quarter and full-year results for 2025 after the market closed Thursday. Its shares fell 2% in after hours trading.

The airline reported adjusted fourth-quarter earnings of $0.43 per share, beating the $0.11 expected by Wall Street analysts polled by FactSet. Its Q4 passenger revenue climbed 2% to $3.25 billion.

For the current quarter, Alaska guided for a 1% to 2% increase in capacity and an adjusted loss of $1.50 to $0.50 per share, compared to the $0.77 loss per share expected by analysts. The airline forecast full-year earnings of between $3.50 and $6.50 per share for 2026. The $5 per share midpoint falls short of analyst estimates of $5.52.

“To hit the higher end of our guidance range we would require sustained macroeconomic recovery in 2026, at or improving on trends seen in the first three weeks of the year, and for fuel prices to stabilize,” the company said in its report.

Earlier this month, the carrier placed its largest ever plane order, securing 110 Boeing jets to support its international growth ambitions. It plans to add flights to Rome, London, and Iceland this summer, and has said it will boost its premium seat offerings this year — in-line with a wider trend of travel trends reflecting a “K-shaped economy.”

Intel Logo In front of Building

Intel slumps after Q1 guidance disappoints

The bad outlook offset strong Q4 results.

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Plug Power jumps amid surge in call activity as CEO Andy Marsh hosts AMA

Plug Power surged on Thursday, jumping nearly 17% amid elevated call activity as outgoing CEO Andy Marsh hosted an “ask me anything” on the r/PlugPowerStock subreddit.

As many as 192,581 call options changed hands, more than 4x the 20-day average — call options with a strike price of $4 that expire in mid-June were the most active contract.

Marsh’s appearance was aimed at building support for the board’s recommendations that its investors vote in favor of three proposals at a special meeting of shareholders slated for next week. These proposals include: allowing votes to be decided by a majority of voters rather than a majority of shareholders, enabling an increase in the company’s share count, and a third measure to delay this special meeting in the event that there aren’t enough votes for either of those two proposals to pass.

During the session, Marsh made the following points:

  • Management really doesn’t want to have to do a reverse stock split, but would feel forced to do so if the second proposal fails to pass. Per a recent filing from Plug, “Without additional authorized shares, the Company will not be able to: meet its contractual obligations to increase authorized shares of common stock by February 28, 2026; raise capital necessary for operations and growth; and execute on its business plans and strategy.”

  • Plug plans to lean even more into opportunities to offer power to AI data center customers, with Marsh writing that incoming CEO Jose Luis Crespo will offer more details on this in a follow-up AMA scheduled for March.

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Meta shares rally as Jefferies says it’s a bargain relative to Mag 7 peers

Shares of Meta rallied over 5% on Thursday, as Jefferies analyst Brent Thill doubled down on his buy rating for the company, calling the stock a relative bargain compared to its Magnificent 7 peers. The analyst set a price target of $910, well above the $645 where the stock is trading today.

News out of the World Economic Forum this week that Meta’s first models from its revamped AI teams are very goodaligns with Thill’s argument that the company is well positioned to get back in the AI race with the “all-star model,” which is expected to be released in the first half of the year.

Recent cuts to Meta’s Reality Labs also signal that the company is focusing its spending where it matters. The Jefferies note added that the recent monetization of Threads via ads will help boost revenue.

Next week, Meta reports its fourth-quarter earnings, and Thill expects that even if the company raises its 2026 capital expenditure outlook, investors won’t be spooked, as the company has been clear that spending may continue to be high.

Recent cuts to Meta’s Reality Labs also signal that the company is focusing its spending where it matters. The Jefferies note added that the recent monetization of Threads via ads will help boost revenue.

Next week, Meta reports its fourth-quarter earnings, and Thill expects that even if the company raises its 2026 capital expenditure outlook, investors won’t be spooked, as the company has been clear that spending may continue to be high.

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