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Eli Lilly rises after earnings, sales blow past Wall Street’s expectations

The company sold $6.5 billion worth of Mounjaro in this most recent quarter, $1 billion more than the Street was expecting.

J. Edward Moreno

Eli Lilly rose after it reported earnings and revenue that beat Wall Street expectations, driven by better-than-expected sales of its blockbuster diabetes shot Mounjaro.

The company reported adjusted earnings per share of $7.02, compared to the $5.89 analysts polled by FactSet were expecting. It also reported $17.6 billion in sales, versus the $16 billion the Street was penciling in. Both its top- and bottom-line results were better than every analyst polled by Bloomberg had projected.

The drugmaker’s sales growth is largely driven by its diabetes and weight-loss shots, Mounjaro and Zepbound. The company sold $6.5 billion worth of Mounjaro in the latest quarter, $1 billion more than the Street was expecting.

Lilly raised its full-year adjusted profit outlook to between $23 and $23.70 per share, up from its previous guidance of $21.75 to $23 a share. It now expects annual revenue to hit between $63 billion and $63.5 billion, up from its previous guidance of $60 billion to $62 billion. 

Tirzepatide, the active ingredient in Lilly's Mounjaro and Zepbound, is now the most-sold medicine in the world, surpassing Merck'scancer therapy, Keytruda, this year.

But despite having some of the bestselling pharmaceuticals on the market, the company is underperforming the broader market for the year, as uncertainty over tariffs and drug pricing roils the industry.

The company has doubled down on direct-to-consumer sales for Zepbound, its popular weight-loss drug that is often not covered by insurance. It offers cheaper cash-pay versions for patients bypassing insurance, and Wednesday announced it would partner with Walmart to distribute the drug.

Brian Mulberry, a portfolio manager at Zacks Investment Management, said that while Lilly's fundamentals are solid, expectations remain high. In its last quarterly report, its earnings beat was overshadowed by trial results that disappointed Wall Street.

"For an investor, this appears like a growth-at-a-premium story: the rewards could be substantial if execution remains strong and the pipeline delivers, but the risks are elevated given high expectations and external headwinds," Mulberry said.

The search for the next blockbuster weight-loss drug is well underway, with Lilly, Novo and several others working on new injectables and the next frontier: pills, which are cheaper to manufacture and could be more inviting for those scared of needles.

Meanwhile, Novo andPfizer are in a bidding war for Metsera, a small biotech working on next-gen GLP-1s.

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Shares of United Airlines are rising after the bell on Tuesday, following the release of the carrier’s fourth-quarter and full-year earnings report.

United posted adjusted earnings per share of $3.10 in Q4, above the $2.92 per share expected by Wall Street analysts polled by Bloomberg. Sales of $15.4 billion were roughly in line with the consensus estimate.

The airline also:

  • Forecast full-year earnings per share between $12 and $14, bracketing Wall Street’s call for $13.04. For Q1, management sees EPS between $1.00 and $1.50, the midpoint of which is above the $1.16 expected by Wall Street.

  • Booked $13.93 billion in passenger revenue on the quarter, up nearly 5% year over year.

“Strong revenue momentum has continued into 2026,” according the company’s press release. “The week ending January 4th was the highest flown revenue week in United history, and the week ending January 11th was the highest ticketing week and the highest week for business sales in United history.”

UAL’s premium ticket revenue climbed 9% compared to a 7% increase in basic economy revenue. The “K-shaped economy” has become increasingly visible in travel trends at major US airlines. Last week, Delta’s revenue from first-class and business passengers eclipsed its main cabin revenue for the first time.

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POET Technologies nears multiyear high on strong call demand after flagship product wins award

POET Technologies is surging on heavy volumes and high call demand after announcing that it won a Product Innovation Award at China’s Infostone awards.

The honor went to the optical communications company’s flagship product, the Teralight, which uses light to move data between chips.

“Unveiled less than a year ago at the 2025 OFC Conference, POET Teralight has driven commercial interest in the Company because of its highly integrated design and complete optical system-on-chip architecture that simplifies module development,” per the press release.

This award may be the latest excuse to buy the stock, which is up over 40% year to date.

Call activity is elevated, with nearly 37,000 having changed hands as of 10:55 a.m. ET, well above the 20-day average of 28,030 for a full session. Shares are approaching their multi-year high of $9.41.

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