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Pfizer's big year

Pfizer's big year

It's likely that a good proportion of you reading this newsletter received a Pfizer-BioNTech COVID-19 vaccine at some point in the last 18 months.

For Pfizer, those billions of doses have translated into a record financial performance, with the COVID-19 vaccine (COMIRNATY) bringing in $36.8bn last year — more than any pharmaceutical product has ever sold in a single year.

Incredibly, Pfizer's 2022 is likely to be even better than its 2021, as the company's COVID pill, Paxlovid, hits the market. Indeed, Pfizer announced this week it expects Paxlovid to contribute an incremental $22bn in revenues next year, with the original COVID vaccine good for another $32bn.

The pharmaceutical industry is a unique one, not just because its products can save lives, but because the economics are so unlike any other. Researching, developing and getting drugs approved is an unbelievably long and expensive task. But once achieved, the marginal costs are usually only a fraction of the end sales price — Pfizer incurred just $31bn of direct costs for its $81bn of sales.

Half full, half empty

Whatever your political persuasion, it's easy to reframe these results in a way that pleases. Pandemic profiteering by big pharma? Or the market's solution to a huge problem that the world needed solving? Take your pick.

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Paramount+ wants to look a lot more like TikTok, leaked documents reveal

Larry Ellison’s Oracle just took a 15% stake in TikTok’s US arm. David Ellison’s Paramount streaming service could soon look a lot more like it.

According to leaked documents seen by Business Insider, Paramount+ is planning a big push into short-form, user-generated video in the vein of the addictive feeds of TikTok, Instagram Reels, and YouTube Shorts.

Per Business Insider, the documents reveal that short-form videos are a top priority for the streamer in the first quarter of 2026, and executives are working on adding a personalize feed of clips to the mobile app.

The move would follow similar mobile-centric plans from Disney, which earlier this month announced that it would bring vertical video to Disney+ this year, and Netflix, which during its earnings call said it would revamp its mobile app toward vertical video feeds and expand its short-form video features.

Streamers are increasingly competing for user attention with popular apps. YouTube is regularly the most popular streaming service by time spent.

Per Business Insider, the documents reveal that short-form videos are a top priority for the streamer in the first quarter of 2026, and executives are working on adding a personalize feed of clips to the mobile app.

The move would follow similar mobile-centric plans from Disney, which earlier this month announced that it would bring vertical video to Disney+ this year, and Netflix, which during its earnings call said it would revamp its mobile app toward vertical video feeds and expand its short-form video features.

Streamers are increasingly competing for user attention with popular apps. YouTube is regularly the most popular streaming service by time spent.

The Memorial Tournament presented by Workday - Previews

Starbucks’ CEO, Brian Niccol, made $30.9 million in 2025

That includes $997,392 in expenses related to his use of the company’s private jet.

Barnes & Noble Store

Bolstered bookseller Barnes & Noble is planning a major expansion and potential IPO

One of the hottest IPOs of the year could be a century-old bookstore that Amazon almost killed.

Nathan's Famous restaurant on Coney Island

Iconic hot dog brand Nathan’s Famous just sold for $450 million

Packaged meat company Smithfield Foods has agreed to acquire the historic Coney Island staple — best known for its annual hot dog eating contest — in an all-cash deal.

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