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Woman’s Hand in Medicine Cabinet
Woman’s hand in medicine cabinet

PBM revenue swells along with rising drug costs

Collectively, the four biggest pharmacy benefit managers raked in $150 billion in revenue in the first three months of 2025, reflecting higher spending on medications.

J. Edward Moreno

Pharmacy benefit managers owned by major insurances companies raked in swelling revenues in the first quarter of this year amid growing prescription volumes for more expensive specialty medications, like popular GLP-1 weight-loss drugs.

The four biggest insurance companies — Cigna, UnitedHealth, CVS’s Aetna, and Elevance Health — each have their own PBM. Collectively, the four biggest PBMs made $150 billion in revenue in the first three months of 2025, reflecting higher spending on medications.

Vertically integrated PBMs (those owned by an insurance company) have been criticized over potential conflicts of interest and lack of competition, sparking pushback from lawmakers. The companies say this allows them to get better deals for patients and rein in exuberant prices from drugmakers.

Notably, this quarter CVS announced that it reached a deal with Novo Nordisk to “increase access” to its blockbuster diabetes and weight-loss drugs, Ozempic and Wegovy. This led Eli Lilly, which makes competing weight-loss and diabetes drugs, to fall, because it suggests one of the largest insurers will be pushing patients toward its competitors’ products.

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OpenAI’s ARR reached over $20 billion in 2025, CFO says

Sam Altman’s $500 billion artificial intelligence behemoth hit a major financial milestone last year, according to a new blog post over the weekend from OpenAI CFO Sarah Friar, as the company confirmed it had hit a more than $20 billion annual revenue run rate at the end of 2025.

Elsewhere in the blog post, Friar spent time addressing the company’s shifting goals, referencing plans to “close the distance between where intelligence is advancing and how individuals, companies, and countries actually adopt and use it.” As has become customary in the AI company press release genre, the CFO was also keen to tout the unending growth of the business, writing:

  • Both our Weekly Active User (WAU) and Daily Active User (DAU) figures continue to produce all-time highs. This growth is driven by a flywheel across compute, frontier research, products, and monetization.

  • Compute grew 3X year over year or 9.5X from 2023 to 2025: 0.2 GW in 2023, 0.6 GW in 2024, and ~1.9 GW in 2025.

And, perhaps most importantly for current backers and those keeping an eye on the private company before its rumored mega IPO:

  • Revenue followed the same curve growing 3X year over year, or 10X from 2023 to 2025: $2B ARR in 2023, $6B in 2024, and $20B+ in 2025. This is never-before-seen growth at such scale.

That latest figure has certainly set tongues in the tech world wagging, just as the company announced it would begin rolling out ads to free and ChatGPT Go users. It also puts the chatbot giant a fair way ahead of competitors like Anthropic, the company behind Claude.

OpenAI Anthropic ARR race
Sherwood News

Elsewhere in the blog post, Friar spent time addressing the company’s shifting goals, referencing plans to “close the distance between where intelligence is advancing and how individuals, companies, and countries actually adopt and use it.” As has become customary in the AI company press release genre, the CFO was also keen to tout the unending growth of the business, writing:

  • Both our Weekly Active User (WAU) and Daily Active User (DAU) figures continue to produce all-time highs. This growth is driven by a flywheel across compute, frontier research, products, and monetization.

  • Compute grew 3X year over year or 9.5X from 2023 to 2025: 0.2 GW in 2023, 0.6 GW in 2024, and ~1.9 GW in 2025.

And, perhaps most importantly for current backers and those keeping an eye on the private company before its rumored mega IPO:

  • Revenue followed the same curve growing 3X year over year, or 10X from 2023 to 2025: $2B ARR in 2023, $6B in 2024, and $20B+ in 2025. This is never-before-seen growth at such scale.

That latest figure has certainly set tongues in the tech world wagging, just as the company announced it would begin rolling out ads to free and ChatGPT Go users. It also puts the chatbot giant a fair way ahead of competitors like Anthropic, the company behind Claude.

OpenAI Anthropic ARR race
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